Difluoroacetic acid

Difluoroacetic acid

Names
IUPAC name 2,2-Difluoroethanoic acid
Other names 2,2-Difluoroacetic acid DFA
Identifiers
Jmol-3D images	Image
SMILES C(C(=O)O)(F)F
Properties
Chemical formula	C2H2F2O2 CHF2COOH
Molar mass	96.033 g/mol
Appearance	Colorless liquid
Odor	Odorless
Density	1.526 g/cm3 (at 25 °C)
Melting point	−1 °C (30 °F; 272 K)
Boiling point	132–134 °C (270–273 °F; 405–407 K)
Solubility in water	Miscible
Solubility	Miscible with alcohols
Acidity (pKa)	1.13
Hazards
Safety data sheet	Sigma-Aldrich
Flash point	78 °C (172.4 °F; 351 K)
Related compounds
Related compounds	Acetic acid Fluoroacetic acid Trifluoroacetic acid
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Difluoroacetic acid is a chemical compound with chemical formula CHF₂COOH.

Properties

Chemical

Difluoroacetic acid reacts with bases to form the corresponding difluoroacetate salts.

Physical

Difluoroacetic acid is a colorless liquid, miscible with water and alcohols.

Availability

DFA is sold by lab suppliers.

Preparation

Can be prepared by refluxing potassium fluoride with dichloroacetic acid.

Projects

• Make difluoroacetate salts
• Compound collecting

Handling

Safety

Difluoroacetic acid is toxic, though less so than its monofluoroacetic derivate. Chronic exposure has been linked to nerve and liver damage.

Storage

In closed bottles, with a PTFE seal and a hazardous chemical label.

Disposal

Should be neutralized with a base. The resulting salts should be taken to waste disposal facilities or recycled.

References

Relevant Sciencemadness threads

• Difluoroacetic acid