Sodium orotate

Sodium orotate

Names
IUPAC name Sodium 2,4-dihydroxypyrimidine-6-carboxylate
Other names Sodium uracil-6-carboxylate
Identifiers
CAS Registry Number	154-85-8
Jmol-3D images	Image
SMILES n1c(O)nc(O)cc1C(=O)O[Na]
Properties
Chemical formula	NaC5H3N2O4
Molar mass	178.085 g/mol
Appearance	White powder
Odor	Odorless
Melting point	Decomposes
Boiling point	Decomposes
Solubility in water	0.294 g/100 ml (25 °C)
Solubility	Insoluble in methanol, ethanol
Vapor pressure	~0 mmHg
Hazards
Safety data sheet	Sigma-Aldrich
Related compounds
Related compounds	Orotic acid Sodium uranyl zinc acetate
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Sodium orotate, NaC₅H₃N₂O₄, is the sodium salt of orotic acid, a metabolic intermediate and chelating agent for certain cations. It is of particular interest as a salt of sodium with a very low solubility in water.

Properties

Chemical

Sodium orotate decomposes at high temperatures.

Physical

Sodium orotate is a white solid, poorly soluble in water.

Availability

Sodium orolate is sold by chemical suppliers.

Preparation

While sodium orotate is not generally available itself OTC, other salts of orotic acid are available as nutritional supplements, particularly magnesium orotate. With the exception of the equally insoluble potassium orotate, these salts will react with sodium chloride in water to precipitate sodium orotate.

Alternatively, it can be prepared by mixing hot aq. solutions of orotic acid and sodium carbonate.

Projects

• Make orotic acid

Handling

Safety

Sodium orotate is generally inert and not expected to pose health or environmental hazards in reasonable quantities.

Storage

In closed plastic or glass bottles.

Disposal

Due to its low solubility and high sodium content mean that it should not flow down a drain or be allowed to mix with soil, as excess sodium is harmful to plants. However, unless one disposes of very large amounts of this compound, this isn't always a problem.

References

• Gravimetric determination of sodium and potassium with N,N-dialkylethanolammonium orotates

Relevant Sciencemadness threads

• Ways to precipitate sodium ions?