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Author: Subject: Iproniazid analog?
stygian
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[*] posted on 5-9-2005 at 13:58
Iproniazid analog?

Iproniazid (isonicotinic acid isopropyl hydrazide), the first MAO inhibitor, uses 4-pyridinecarboxylic acid (isonicotinic acid). Could the 3-substituted acid (nicotinic acid) be used instead and possibly still retain activitywithout becoming more hepatotoxic (iproniazid is bad enough), or possibly less toxic?
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stygian
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[*] posted on 8-9-2005 at 12:28


Would I get more replies if i said isomer instead of analog?
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