| Pages:
1
2 |
Klute
International Hazard
Posts: 1378
Registered: 18-10-2006
Location: France
Member Is Offline
Mood: No Mood
|
|
I don't think that the kind of reaction you would like to do at such a scale... THF and oxidizers at mmol scale is already hazardous, doing it in
drums is asking for trouble... Imagine a whole drum going off...
Do some bungee jumping instead! 
|
|
|
MagicJigPipe
International Hazard
Posts: 1554
Registered: 19-9-2007
Location: USA
Member Is Offline
Mood: Suspicious
|
|
I read the back of some PVC cements and noticed that nearly all of them contained acetone, 2-butanone and cyclohexanone.
Since these obviously cannot be seperated by fractional distillation in a normally equipped home lab I don't see the point in obtaining THF from this
source. That's about 100ml per can and 3-4 dollars per can... Well, now that I wrote that I see now. If it could be seperated economically then it
would be worth it. I still have yet to find a supplier that will sell THF to individuals. I would love to have some for Grignards.
I see that y-butyrolactone can be obtained from THF. What uses does it have in the lab?
"There must be no barriers to freedom of inquiry ... There is no place for dogma in science. The scientist is free, and must be free to ask any
question, to doubt any assertion, to seek for any evidence, to correct any errors. ... We know that the only way to avoid error is to detect it and
that the only way to detect it is to be free to inquire. And we know that as long as men are free to ask what they must, free to say what they think,
free to think what they will, freedom can never be lost, and science can never regress." -J. Robert Oppenheimer
|
|
|
Nicodem
Super Moderator
Posts: 4230
Registered: 28-12-2004
Member Is Offline
Mood: No Mood
|
|
| Quote: | Originally posted by MagicJigPipe
I see that y-butyrolactone can be obtained from THF. What uses does it have in the lab? |
Which, THF of gamma-butyrolactone? THF is the aprotic relatively polar solvent of choice for certain reactions where other more polar aprotic solvents
which generally have electophilic centers can not be used (since they would react themselves; for example, for Grignards like you mentioned or
oraganolithium reactions, etc.).
gamma-Butyrolactone is also an even more polar aprotic solvent that is very good at dissolving certain compounds, but is very, very rarely used. We
only have one bottle at our lab and I never saw anybody ever considering its use. I can't imagine a reaction where there would be no alternative for
gamma-butyrolactone as solvent. Though it can also be used as reagent/substrate for reactions in which case it has no alternatives.
…there is a human touch of the cultist “believer” in every theorist that he must struggle against as being
unworthy of the scientist. Some of the greatest men of science have publicly repudiated a theory which earlier they hotly defended. In this lies their
scientific temper, not in the scientific defense of the theory. - Weston La Barre (Ghost Dance, 1972)
Read the The ScienceMadness Guidelines!
|
|
|
Methyl.Magic
Hazard to Others
Posts: 139
Registered: 14-5-2007
Member Is Offline
Mood: No Mood
|
|
GBL is more used as substrate (i.e. for making 4-chlorobutyryl chloride) than as solvent...
GBL is very hard to find because it's a watched and scheduled chemical. NMP is prefered instead of GBL as solvent.
|
|
|
| Pages:
1
2 |
![[*]](images/xpblue/default_icon.gif){kind=icon}
