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trilobite
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A method of acylating benzodioxole I rarely see mentioned is published in WO9639133 by J. Peyton III and A. Shulgin. They use molecular iodine to
catalyze the reaction between benzodioxole and propionic anhydride.
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chemrox
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anyway doesn't the deactivating nature of the bridged ether groups make F/C not very practical? I think the MDO groups put the ring C's to sleep at
least with respect to electrophillic reax.
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Sergei_Eisenstein
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| Quote: | | A method of acylating benzodioxole I rarely see mentioned is published in WO9639133 by J. Peyton III and A. Shulgin. They use molecular iodine to
catalyze the reaction between benzodioxole and propionic anhydride. |
There is a similar method to be found in the literature: JACS 76(20) (1954) 5150-5150 (DOI: 10.1021/ja01649a046).
| Quote: | | anyway doesn't the deactivating nature of the bridged ether groups make F/C not very practical? I think the MDO groups put the ring C's to sleep at
least with respect to electrophillic reax. |
Why would it be deactivating? It can - more or less - be compared to veratrol, which is also considered an "activated arene".
damnant quod non intelligunt
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Polverone
Now celebrating 21 years of madness
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Thread Split
20-3-2010 at 10:38 |
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