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Globey
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I'm more interested in the de-syntheses if things like diphenhydramine. What reagents can one tease apart
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Picric-A
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I would just like to update this thread.
After my LONG efforts at trying to synthesise dimethylethanolamine i have found out it is extremly cheap and readily available as a vitamin!!
http://en.wikipedia.org/wiki/Dimethylethanolamine
If only i had found this out sooner!
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mario840
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but did you succesfull synthesised it ??
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Picric-A
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Yes, by reacting 2-chloroethanol with dimethylamine under reflux. Yields ok but cost of raw materials was much higher than the cost of buying the
vitamin.
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mario840
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is there any patent for making dimethylethanolamine from 2-chloroethanol and dimethylamine ? or you just work it out ?
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Picric-A
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I didnt find a patent for this specific reaction however there were many patents with similar reactions.
2-chloroethanol was refluxed with an excess of a solution of dimethylamine in ethanol, followed by evaporation and fractionating the oil residue
udner vacuum.
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mario840
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thanks men !! 
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