AvBaeyer
National Hazard
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Registered: 25-2-2014
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Heterocyclic Drugs Synthesis Review
I came across this review which may be known to some of you. I found it reasonably interesting because of the broad spectrum of organic synthesis
covered. Unfortunately, several of the reaction schemes contain errors. However, if you have a good eye and a reasonable knowledge of organic
chemistry, they should be obvious.
Enjoy it for what is worth.
AvB
Attachment: Drugs containing nitrogen heterocycles.pdf (6.2MB)
This file has been downloaded 408 times
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Dr.Bob
International Hazard
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Thanks for posting this, always love seeing reviews with real chemistry. And most drugs have a nitrogen in them somewhere, with a few exceptions.
Don't see much good chemistry in the current job. We seem to get mostly synthesis of stuff with poor experimentals and bad properties.
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Pumukli
National Hazard
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Thanks for the share!
A few interesting (long forgotten) steps here and there. 
But: "so many possibilities and so little time"! 
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