xiangming660427
Harmless
Posts: 1
Registered: 30-8-2018
Member Is Offline
|
|
2-Chlorophenyl cyclopentyl ketone via Grignard Reagent
Hi my friends.
Here I am trying the method posted in another post to make 2-Chlorophenyl cyclopentyl ketone.
http://www.sciencemadness.org/talk/viewthread.php?tid=154038
Instead of synthesizing the Grignard reagent, I purchased it directly. After running all synthesis procedures, I extracted the mixture with Ethyl
Acetate and then it turned out to be dark and sticky. And the yield was pretty low.
Could you provide any assistance?
|
|
|
SuperOxide
Hazard to Others
Posts: 486
Registered: 24-7-2019
Location: Devils Anus
Member Is Offline
|
|
Can you give a little more details on how the procedure went? You said you purchased the Grignard reagent cyclopentylmagnesium bromide
instead of making it yourself from cyclopentyl bromide and magnesium? From what I'm told, ready-made Grignard reagents are pretty sensitive and
usually only purchased by labs who use them in large quantities. Can you share a link to where you got it from?
I haven't done this reaction, but I have been looking into it. Not sure I can help, but I'll try.
|
|
|
![[*]](images/xpblue/default_icon.gif){kind=icon}
