millerxia
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how to synthesis5--methyl-- 3-bromo-pyridine
how to synthesis 3-bromo-5-methylpyridine from 2-amino-3-bromo-5-methylpyridine?
i use 2-amino-3-bromo-5-methylpyridine as the materials. Here is my experiment:
1 mol 2-amino-3-bromo-5-methylpyridine was added to 60%H2SO4 solution , then saturated NaNo2 was addes in small portions ,temperature been
maintainted under 0 centigrade.
Then hypophosphorous acid was add, the temperature still under 0 centigrade.
afer 2 hours , i analysis by GC, fond that we only get diaoztizing salt, there is no 3-bromo-5-methylpyridine 
Anyone who can tell me, how to remove the amino in the pyridine ring? Waiting for your help, thanks a lot!
Enclosed is the reaction
Attachment: reaction.rar (914B)
This file has been downloaded 452 times
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millerxia
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anyone who can help me ? thanks anyway!
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not_important
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Can't read that file you attached, system thinks its a save file from some game.
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chemrox
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I need an unrar program .. rarzilla sucks big time
"When you let the dumbasses vote you end up with populism followed by autocracy and getting back is a bitch." Plato (sort of)
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Nicodem
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| Quote: | Originally posted by millerxia
afer 2 hours , i analysis by GC, fond that we only get diaoztizing salt, there is no 3-bromo-5-methylpyridine |
You detected the diazonium salt with GC? 
How is a diazonium salt supposed to come trough the GC column?
…there is a human touch of the cultist “believer” in every theorist that he must struggle against as being
unworthy of the scientist. Some of the greatest men of science have publicly repudiated a theory which earlier they hotly defended. In this lies their
scientific temper, not in the scientific defense of the theory. - Weston La Barre (Ghost Dance, 1972)
Read the The ScienceMadness Guidelines!
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