stimo-roll
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phenylacetonitrile synt from Pihkal
Hi. Interesting reaction for preparation phenylacetonitriles - http://www.erowid.org/library/books_online/pihkal/pihkal147.... Substituted bromobenzene reacted wia strong base (LDA) give yne-derevate, which
reacts wia acetonitrile give subst-phenylacetonitrile. Anybody know this type reaction examples in literature? Can LDA be replaced with t-BuOK?
[Edited on 15-12-2007 by stimo-roll]
[Edited on 15-12-2007 by stimo-roll]
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stoichiometric_steve
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why bother, when it is clearly stated that it is not easy to purify the resulting mixture of products - and the yield is also shitty.
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vulture
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t-BuOK is not basic enough. And we don't like cookery threads here...
One shouldn't accept or resort to the mutilation of science to appease the mentally impaired.
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