arevelacao
Harmless
Posts: 9
Registered: 4-9-2006
Member Is Offline
Mood: No Mood
|
|
Making Tablets / Pills
I would like to presses ascorbic acid in a tablet. I can freely use binders / disintegrants: lactose, microcrystalline cellulose. Stearic acid and
magnesium stearate as lubricants in a dry formulation. And obviously a source of a regular crystalline pharmaceutical grade L-ascorbic acid ~325 mesh.
But it is "impossible" to find any procedure and/or referenced material in the net.
I would be very grateful in sharing this knowledge.
|
|
YT2095
International Hazard
Posts: 1091
Registered: 31-5-2003
Location: Just left of Europe and down a bit.
Member Is Offline
Mood: within Nominal Parameters
|
|
them make Capsules instead
http://www.capsugel.com/
http://www.emptycaps.com/
http://www.capsuleking.com/?gclid=CP
failing that you`ll need a tablet press or a pill roller.
[Edited on 15-10-2006 by YT2095]
\"In a world full of wonders mankind has managed to invent boredom\" - Death
Twinkies don\'t have a shelf life. They have a half-life! -Caine (a friend of mine)
|
|
evil_lurker
National Hazard
Posts: 767
Registered: 12-3-2005
Location: United States of Elbonia
Member Is Offline
Mood: On the wagon again.
|
|
Well if you had a tableter I'm sure the manufacturer could help you out.
But, I hope your not in the USA cause tableters are strictly regulated.
|
|
Darkblade48
Hazard to Others
Posts: 411
Registered: 27-3-2005
Location: Canada
Member Is Offline
Mood: No Mood
|
|
I'm not sure who it was, but I'm pretty sure I saw someone that had a homemade pellet maker; it was of pretty simple construction, just a few parts
that could be picked up at a local hardware store, or the like...
Included is a picture, whoever made this might be able to provide you more information
|
|
Magpie
lab constructor
Posts: 5939
Registered: 1-11-2003
Location: USA
Member Is Offline
Mood: Chemistry: the subtle science.
|
|
Darkblade that is my picture. I made it for making soda-lime pellets, IIRC. It will work fine if you just want to make a few pellets. But if you
want to go into production it would get a little tedious. Search "pellet press" and Magpie if you want to see it in more detail.
The single most important condition for a successful synthesis is good mixing - Nicodem
|
|
Thermal
Harmless
Posts: 41
Registered: 31-1-2004
Member Is Offline
Mood: No Mood
|
|
I remember seeing a setup or two using a hydraulic bottle jack and a machined block/pegboard on that former bee site but damned if I can find it now.
Maybe someone has it archived. - there were three pieces in a frame like a bearing press - a pegboard style block in the top with pegs of steel the
size of the tablet another block with holes drilled all the way through and a third block under that which you could slide out allowing you to push
the pressed pellets through the bottom. The thread had ton's of equations as far as the force required, discussion as to the proper metals required
and required ratios of tableting additives - but that's all that I remember.
Sorry I can't elaborate any more.
Good luck
[Edited on 16-10-2006 by Thermal]
|
|