I'd first mesh the tissue in a meat grinder, for an extended period of time, in the presence of EDTA to keep the Hg in solution. To minimise
preciptates (which will also contain Hg), add a strong detergent such as SDS (to keep the lipids in), and add a cocktail of proteases, lipases, DNA
and RNAses.. This will keep most things in solution. Then centrifuge hard to get rid of insoluble material (which shouldnt contain much Hg), the
supernatant will be a cocktail of things, including your Hg.
Make sure the enzymes are EDTA resistant, i.e. that they don't contain metal ions else you will inactivate them.
Never Stop to Begin, and Never Begin to Stop...
Tolerance is good. But not with the intolerant! (Wilhelm Busch)
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