LexxD
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Nicotine extraction
Hey guys,
I am doing a work for school where I should (theoretically) work out a process to extract nicotine from tobacco. I am not working with it beceaus it
is just to dangerous.
So, I was thinking of an acid/base-extraction.
But when I look that up I get a cristal nicotine HCl. Is there a way to get only nicotine?
I already thank you for just reading this.
And sorry for my bad english..
With kind regard
Lex
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DraconicAcid
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Once you get nicotine hydrochloride, you can react it with a base to give the free amine.
Please remember: "Filtrate" is not a verb.
Write up your lab reports the way your instructor wants them, not the way your ex-instructor wants them.
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LexxD
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So if I just let it react with, let's say, NaOH or KOH, I get nicotine?
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DraconicAcid
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That should work. The nicotine is very water soluble, though, so it won't precipitate from the solution.
Please remember: "Filtrate" is not a verb.
Write up your lab reports the way your instructor wants them, not the way your ex-instructor wants them.
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LexxD
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Oke, thank you very much. You've helped me a lot!
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khlor
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Theorically you could get high concentration of nicotine by reacting nicotine hydrochloride with copper oxide that will give you water and copper
chloride I, once you precipitate the copper chloride I from de solution, what is left over is only nicotine with traces of copper chloride.
"NOOOOOO!!! The mixture is all WROOOOOOONG!"
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LexxD
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So I would just let the Copper chloride percipitate, then, the rest is nicotine with some traces of copper chloride?
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DraconicAcid
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I would be surprised if an amine like nicotine didn't coordinate to copper(I) or copper(II).
Please remember: "Filtrate" is not a verb.
Write up your lab reports the way your instructor wants them, not the way your ex-instructor wants them.
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khlor
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Are you talking about nicotine complex?
"NOOOOOO!!! The mixture is all WROOOOOOONG!"
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benzylchloride1
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Use picric acid to precipitate the picrate.
Amateur NMR spectroscopist
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Chemosynthetic
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I am probably too late for the assignment, but flash chromatography would be my answer. Way too many complex impurities in biological samples for
recrystallization or the like to get you assured quality control or even shelf life, generally.
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