Sciencemadness Discussion Board

wondering about mechanism

Elmoush3 - 18-7-2017 at 02:21

hi chemists:
i did face aproblem concerning artemether (an antimalaria drug) stability problrm,,, when it degraded in water,,,
artemether has a endoperoxide ring
https://en.wikipedia.org/wiki/Artemether#/media/File:Artemet...
is it possible for o-demethylation to occur in nirmal sitution and non acidic ph
in case i use alcohol will the degradiation presist,,,

thnx in advance

[Edited on 18-7-2017 by Elmoush3]