Sciencemadness Discussion Board

Reduction of Alpha-Isonitrosopropiophenone

victory - 9-3-2016 at 14:27

Would reduction of Alpha-Isonitrosopropiophenone be possible using TinDichloride??

karlos³ - 9-3-2016 at 14:41

That is an exceptionable hard to reduce substrate, it depends on which functional group you want to reduce.
To what do you want to reduce it, to the nitrosophenylpropionylalcohol?
Or straight the way to the aminoalcohol?
Or even further to the aminoalkane?

With Tin, no way.

clearly_not_atara - 9-3-2016 at 15:13

Exceptionally? Not easy, certainly, but this doesn't even register on the list of things which are hard to reduce (consider, say, phosphoric acid).

I think, based on my remarkable intuition, that OP wants to produce the aminoketone, the CI-controlled substance cathinone. This can be done by █████████████ in ██████ or by ███████████████████ with ████████ in a solvent such as ██████ or ██████. Unfortunately, discussing how to synthesize this compound is against the rules.

[Edited on 9-3-2016 by clearly_not_atara]