Hello everyone!
I found an chinese article about chloromethylation of 1,3-Benzodioxole in the presence of micellar catalysts.
I don't understand this language, need translation.
Can anybody help?
Abstract:
Benzodioxole was monochloromethylated directly by aqueous formaldehyde and hydrogen chloride gas in CCl4 in the presence of quaternary ammonium salts.
With hexadecyltrimethylammonium bromide at temperature 60~65 ℃ and for 15 hours of reaction, 1,3-benzodioxole was converted to piperonyl
chloride with conversion more than 98% and selectivity up to 97%. The method has advantages of high selectivity, high conversion, negligible
by-products and easy workup of the main product.
Unfortunately neither do I. Have you tried online translation services?
Be sure to also check out bromomethylation. There are references using biphasic systems and also mono-phasic HBr/AcOH systems. I have made a few
experiments on para-dimethoxy-benzene and they gave me lots of bis-bromomethylarene product (definitely) and I think also lots of bis-aryl-methane
product (not unambiguously identified, but low nominal yield and high mp seems to indicate that). The best run so far was a biphasic system
without PTC.
Anyway, good luck - very interesting topic.
[Edited on 6-2-2014 by turd]GroovyDoo - 6-2-2014 at 12:54
Yes, I tried online translation services - results is terrible
Feeling like an epigraphiest...
