I am doing a work for school where I should (theoretically) work out a process to extract nicotine from tobacco. I am not working with it beceaus it
is just to dangerous.
So, I was thinking of an acid/base-extraction.
But when I look that up I get a cristal nicotine HCl. Is there a way to get only nicotine?
I already thank you for just reading this.
And sorry for my bad english..
With kind regard
Lex DraconicAcid - 29-1-2014 at 12:34
Once you get nicotine hydrochloride, you can react it with a base to give the free amine.LexxD - 29-1-2014 at 12:39
So if I just let it react with, let's say, NaOH or KOH, I get nicotine? DraconicAcid - 29-1-2014 at 12:43
That should work. The nicotine is very water soluble, though, so it won't precipitate from the solution.LexxD - 29-1-2014 at 12:44
Oke, thank you very much. You've helped me a lot! khlor - 29-1-2014 at 12:59
Theorically you could get high concentration of nicotine by reacting nicotine hydrochloride with copper oxide that will give you water and copper
chloride I, once you precipitate the copper chloride I from de solution, what is left over is only nicotine with traces of copper chloride.LexxD - 29-1-2014 at 13:08
So I would just let the Copper chloride percipitate, then, the rest is nicotine with some traces of copper chloride? DraconicAcid - 29-1-2014 at 13:13
I would be surprised if an amine like nicotine didn't coordinate to copper(I) or copper(II).khlor - 29-1-2014 at 13:20
I would be surprised if an amine like nicotine didn't coordinate to copper(I) or copper(II).
Are you talking about nicotine complex?benzylchloride1 - 31-1-2014 at 01:20
Use picric acid to precipitate the picrate.Chemosynthetic - 15-2-2014 at 13:31
I am probably too late for the assignment, but flash chromatography would be my answer. Way too many complex impurities in biological samples for
recrystallization or the like to get you assured quality control or even shelf life, generally.
