Dear all
I am trying on air / aerobic oxidation of Oxidation of 2-octanol or 2-octanone to hexanoic acid without using nitric acid.
do you have suggestionsbbartlog - 13-11-2013 at 05:45
How would that even work? Assuming you cleave the final carbon and oxidize the remaining chain (via the haloform reaction, maybe), you still have
heptanoic acid, which is one carbon atom longer than what you're aiming for.blogfast25 - 13-11-2013 at 06:01
Can't work, belongs in organics section.Nicodem - 13-11-2013 at 07:06
I cannot say it can work because I did not bother checking the literature, but it might work by the Willgerodt-Kindler reaction followed by the
thioamide hydrolysis. There are other ways, but none is really practical, certainly not for something so simple and cheap.
PS: Vinda, please read the forum guidelines. Threads opened without any reference belong to the Beginnings section.eidolonicaurum - 9-1-2014 at 05:34
Air is not a sufficiently powerful oxidising agent to oxidise a ketone to a carboxylic acid. You would need a much, much more powerful oxidising
agent.
In order to convert the heptanoic acid formed into hexanoic, you could to a Hofmann reduction.
