Sciencemadness Discussion Board

how can i dissolved amino acid

cazruto - 29-4-2012 at 07:47

how can i dissolved amino acid in organic solvent but without alcohol and any OH group and DMF, MEK, DMSO cant dissolved.
what i should do please help me research's

Arrhenius - 29-4-2012 at 19:30

You need to give more information than this. What are you trying to do? DMF, DMSO, AcOH, NMP are good choices. Aqeous NaOH or HCl can also good choices. Just depends what you're doing.

Hexavalent - 30-4-2012 at 10:46

I agree with Arrhenius - it completely depends on what amino acid and what you intend to do with it as your experimental.

This should probably be in beginnings, so I've inboxed the mods asking them.

cazruto - 30-4-2012 at 18:27

Quote: Originally posted by Hexavalent  
I agree with Arrhenius - it completely depends on what amino acid and what you intend to do with it as your experimental.

This should probably be in beginnings, so I've inboxed the mods asking them.


dear Arrhenius
i just dissolved amino acid in without -OH group in organic solvent and also not use water inorganic liquid, but its cant dissolved

Rich_Insane - 30-4-2012 at 21:29

Which amino acid? They're all a bit different from each other. I suspect that the COOH and amine group make it susceptible to hydrogen bonding and polar interactions... In general. Tyrosine was always a pain in the ass for me. It only dissolved in water with vigorous autoclavation at high pressure and ~120oC, and even then it precipitated out within the next eight hours.

help me, i dont have any idea

cazruto - 29-5-2012 at 23:15

hello everyone i need your help.
how can i dissolved glycine in without hydroxyl group organic solvent and also not use inorganic solvent its mean not water and any acid, base. please help me and thank you for read

[Edited on 30-5-2012 by cazruto]

bahamuth - 30-5-2012 at 03:37

Quote: Originally posted by cazruto  
hello everyone i need your help.
how can i dissolved glycine in without hydroxyl group organic solvent and also not use inorganic solvent its mean not water and any acid, base. please help me and thank you for read

[Edited on 30-5-2012 by cazruto]


1. How much do you need to dissolve, kinda limits the solvent choices and you should give that information when you ask the question.
2. Can't you have any hydroxyl group, and why?
3. Why not in acids or bases?

If you want to dissolve just a little bit, hot acetone will dissolve some, though I don't remember how much. And if you give more background info, like what you need this solution for, people here might be able to give workaround solutions to your problem.

And I think this belongs in Beginnings.

Hexavalent - 30-5-2012 at 12:32

I agree . . .add a little more detail and explain your 'specifications' for solvent choices and we can help you much more easily.

You probably have to go for highly polar solvents. Acetic acid might work. Vinegar (acetic acid + water) too, if it turns out that you *can* use an acid.

Is this your homework/schoolwork, or a practical experimental problem?

barley81 - 30-5-2012 at 12:44

I think he needs an aprotic solvent. In that case, acetone might work. I saw online that glycine is "slightly soluble" in acetone. It is probably not soluble in DMSO:
Quote:
Amino acid solubility measurements showed that the interactions between glycine and DMSO are highly unfavorable, while the interactions of DMSO with aromatic and hydrophobic side chains are favorable.


DMF or NMP? Just guessing.