Sciencemadness Discussion Board

Isosorbitol Dinitrate

holmes1880 - 12-1-2011 at 09:34

Isosorbitol Dinitrate:

white microcrystals
empirical formula: C6H8N2O8
molecular weight: 236.1
oxygen balance: –54.2%
nitrogen content: 11.87%
melting point: 70 °C = 158 °F (decomposition)
lead block test: 311 cm3/10 g
detonation velocity, confined:
5300 m/s at r = 1.08 g/cm3
deflagration point: 173 °C = 343 °F
impact sensitivity: 1.5 kp m = 15 N m
friction sensitivity: over 16 kp = 160 N
pistil load crackling
Isosorbitol dinitrate serves as an effective cardial medicine (in low percentage mixture with milk sugar; it is more effective than
W PETN). The pure substance is a strong explosive.


Great properties, great stability, but cannot find much on synthesis.

Discuss.

The WiZard is In - 12-1-2011 at 12:26

Quote: Originally posted by holmes1880  
Isosorbitol Dinitrate:

white microcrystals
empirical formula: C6H8N2O8
molecular weight: 236.1
oxygen balance: –54.2%
nitrogen content: 11.87%
melting point: 70 °C = 158 °F (decomposition)
lead block test: 311 cm3/10 g
detonation velocity, confined:
5300 m/s at r = 1.08 g/cm3
deflagration point: 173 °C = 343 °F
impact sensitivity: 1.5 kp m = 15 N m
friction sensitivity: over 16 kp = 160 N
pistil load crackling
Isosorbitol dinitrate serves as an effective cardial medicine (in low percentage mixture with milk sugar; it is more effective than
W PETN). The pure substance is a strong explosive.


Great properties, great stability, but cannot find much on synthesis.
Discuss.



The book you cribbed this from fails to mention that it is an oily liquid.

Synthesis is standard.

Curious dobe I — with all the expls in la book, why chose
this one did you? & byda which edition #1-6?

The WiZard is In - 12-1-2011 at 12:51

Quote: Originally posted by The WiZard is In  
Quote: Originally posted by holmes1880  
Isosorbitol Dinitrate:

white microcrystals
empirical formula: C6H8N2O8
molecular weight: 236.1


The book you cribbed this from fails to mention that it is an oily liquid.
So sez PATR 2700 G82, however.....

The hexa can be made as an oily liquid see Davis or (better) Urbanski.

hissingnoise - 12-1-2011 at 12:55

WiZ, you may be thinking of sorbitol hexanitrate which *is* a syrupy liquid - and isomeric with nitromannite.
But isosorbitol dinitrate has a poor OB, low VoD and the LBT puts it just ahead of sucrose octonitrate!
Great properties - I don't think so?

holmes1880 - 12-1-2011 at 21:05

Hissingnoise,

I'm looking at certain properties such as stability and deflagration points. PETN is at 3Nm for impact stability.....compare this to 15Nm of I.D. I like it. Plus, such a high negative OB gives it a nice room for mixing with AN


@ Wizard

Yes, I think you are confusing it, because it clearly states white microcrystals. Anyways, I need to find an economic way to synthesize it.

[Edited on 13-1-2011 by holmes1880]

TheOrbit - 12-1-2011 at 21:34

for drug "medicine" industrial synthesis one of the common reference is
Pharmaceutical manufacturing encyclopedia
search for it and you will find most of the marketing available drug there

TheOrbit - 12-1-2011 at 21:39

and also it preferable to call it (isosorbide dinitrate).

The WiZard is In - 13-1-2011 at 14:51

Quote: Originally posted by holmes1880  
Hissingnoise,

I'm looking at certain properties such as stability and deflagration points. PETN is at 3Nm for impact stability.....compare this to 15Nm of I.D. I like it. Plus, such a high negative OB gives it a nice room for mixing with AN


Time Magazine 17xi10 named the explosive IMX-101 #43 of
the top 50 inventions of the year.

http://tinyurl.com/4q46l9q
http://en.wikipedia.org/wiki/IMX-101

Run it through DTIC.MIL


The WiZard is In - 13-1-2011 at 15:08

Quote: Originally posted by TheOrbit  
and also it preferable to call it (isosorbide dinitrate).


It is listed as such in The Merck Index.

[87-33-2]

It refs. Prepn. from sorbitol: Goldberg, Acta Physiol. Scand.
15 173 (1948). C.A. 42, 5564 (1948)

TheOrbit - 13-1-2011 at 18:47

Quote: Originally posted by The WiZard is In  
Quote: Originally posted by TheOrbit  
and also it preferable to call it (isosorbide dinitrate).


It is listed as such in The Merck Index.

[87-33-2]

It refs. Prepn. from sorbitol: Goldberg, Acta Physiol. Scand.
15 173 (1948). C.A. 42, 5564 (1948)


i said it is PREFERABLE not a must to be named like this.
and it mentioned under isosorbide dinitrate in Merck Index.



wz.bmp - 496kB

The WiZard is In - 13-1-2011 at 20:22

Quote: Originally posted by TheOrbit  


i said it is PREFERABLE not a must to be named like this.
and it mentioned under isosorbide dinitrate in Merck Index.


What! I see not were we disagree.

Using my God like powers of reference .... I see you used
the 11th 1989 ed of the Merck Index. 'bout the only change
in the current 14th ed. 2006 [#5225] is the addition of its CA #.


Trivia - What were the first few ed's of what is now called The
Merck index labeled?

TheOrbit - 13-1-2011 at 21:10

there is no disagree , everyone has the right to defend its opinion. i post this name because its the common name used for this drug so it will ease search


Quote:

God like powers


i hope that i misunderstood this "STRANGE" sentence !!!!
Quote:

Trivia - What were the first few ed's of what is now called The
Merck index labeled?


sorry , but i didn't get the meaning behind this

holmes1880 - 14-1-2011 at 02:30

@Orbit,

You are right about the name. I found a whole lot more info on it, but synthesis is still a mystery. I did find a place to buy the pills though, so I could potentially do some tests with it to see if its even worthwhile to make.

P.S. Don't pay attention to Wizard, he likes to troll far too often.

TheOrbit - 14-1-2011 at 05:09

there is no problem at all i tried to help only and i think we all try to help here.
if you see the manufacturing encyclopedia you will find this:


ho.bmp - 900kB

The WiZard is In - 14-1-2011 at 07:17

Quote: Originally posted by TheOrbit  

Quote:

Trivia - What were the first few ed's of what is now called The
Merck index labeled?


sorry , but i didn't get the meaning behind this



The 1st 4 editions of what is now know as
The Merck Index were called Merck Index


Byda I posted this 12-1-2011 at 15:26

Synthsis is standard.


djh
----
I though for today.

I would paraphrase Haldane - God must have had an inordinate
fondness for carbon for he has made so many carbon compounds.