Sciencemadness Discussion Board

New local anesthetic (articaine)

guaguanco - 23-1-2004 at 09:59

My dentist used this one on me today. Said it's stronger and shorter acting than lidocaine. Apparently it took forever for the FDA to let it into the US. My mouth is sure numb, so I guess it works.


nice mol.

embezzler - 29-1-2004 at 14:10

that is a complex looking molecule, how new is this drug? do you know which of the functional groups are biologically active or have i got to do my own reading

guaguanco - 29-1-2004 at 15:21

Well, there's such a diversity of local anesthetics nowadays that they don't all fit the same mold.
Here is a good link
http://wiz2.pharm.wayne.edu/module/lanest.html

As far as the complexity: I just got a new Merck Index. This chemical is *nothing* compared to a lot of the pharmaceuticals nowadays...

thanks

embezzler - 29-1-2004 at 16:07

thanks for the link.
is that the 13th ed. or have merck a newer one?
suppose it is not the most complicated but it does have a lot of varied groups attached

guaguanco - 29-1-2004 at 21:23

Yep, 13th edition. My well-worn 8th edition get an honorable retirement.
There's some truly wacky anesthetics nowadays.

gil - 18-1-2007 at 20:16

Intriguingt. Does Stimulate too? The mind ,maybe?Guillermo ?

chiralic - 19-1-2007 at 12:29

Here more information about Articaine...

Comparison of ARTICAINE and LIDOCAINE used as dental local anesthetics
http://www.odont.uio.no/studier/semesterboker/Felles/prosjek...