Originally posted by chemrox
(0.1 mol.) N-benzylpiperazine is dissolved in DCM under Ar atmosphere*. To this is added (0.1) phenylacetaldhyde and (0.2 mol) acetic acid. The
mixture is stirred for a half hour after which (0.15 mol) STAB was added and the whole is stirred for 24 hours. The expected product is
N, N'-diphenethylpiperazine.
*[procedure-pump out the air until the solvent starts to boil and let Ar on. Repeat nine times and maintain slight pressure with an oil bubbler or
baloon] |