Sciencemadness Discussion Board

How can I synthesise 2-methyl-4chlorophenol?

Shadeslayer - 9-11-2018 at 04:13

I need to synthesise MCPA. For that I have managed to synthesis Chloro acetic acid. I can't figure out exactly how to make 2-methyl-4chlorophenol. Can anyone help? Thank you! :)

Metacelsus - 9-11-2018 at 10:46

You can try chlorinating 2-methylphenol (aka o-cresol). This will produce a mixture of the 4-chloro and 6-chloro products, which should be separable.

But why not just buy MCPA? It's widely available as an herbicide.

CuReUS - 10-11-2018 at 08:00

Quote: Originally posted by Shadeslayer  
I can't figure out exactly how to make 2-methyl-4chlorophenol.

using oxone - https://www.tandfonline.com/doi/full/10.1081/SCC-120002013

using bleach -http://nopr.niscair.res.in/bitstream/123456789/18605/1/IJCA%...