Difference between revisions of "Benzocaine"
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Benzocaine is a local anesthetic. | Benzocaine is a local anesthetic. | ||
It is the ethyl ester of PABA or ParaAminoBenzoic Acid. | It is the ethyl ester of PABA or ParaAminoBenzoic Acid. | ||
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{{Chembox | {{Chembox | ||
| Name = Benzocaine | | Name = Benzocaine | ||
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==Properties== | ==Properties== | ||
===Chemical=== | ===Chemical=== | ||
− | + | Benzocaine is the ethyl ester of p-aminobenzoic acid (PABA). It can be prepared from PABA and ethanol[1] by Fischer esterification or via the reduction of ethyl p-nitrobenzoate. Benzocaine is sparingly soluble in water; it is more soluble in dilute acids and very soluble in ethanol, chloroform and ethyl ether. ===Physical=== | |
− | ===Physical=== | + | |
==Availability== | ==Availability== | ||
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==Preparation== | ==Preparation== | ||
− | + | Benzocaine can be prepared by esterfication using 4-aminobenzoic acid and ethanol. It can also be prepared by reduction of ethyl 4-nitrobenzoate to the amine. | |
+ | In industrial practice, the reducing agent is usually iron and water in the presence of a little acid. | ||
==Projects== | ==Projects== | ||
Revision as of 14:40, 27 January 2016
Benzocaine is a local anesthetic. It is the ethyl ester of PABA or ParaAminoBenzoic Acid.
Names | |
---|---|
IUPAC name
Ethyl 4-aminobenzoate
| |
Systematic IUPAC name
Ethyl 4-aminobenzoate | |
Properties | |
C 9 H 11 NO 2 | |
Molar mass | 165.189 g/mol |
Density | 1.17g/cm3 |
Melting point | 89 °C |
Boiling point | 310 °C |
slightly soluble in water. | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
Infobox references | |
(Introduction)
Contents
Properties
Chemical
Benzocaine is the ethyl ester of p-aminobenzoic acid (PABA). It can be prepared from PABA and ethanol[1] by Fischer esterification or via the reduction of ethyl p-nitrobenzoate. Benzocaine is sparingly soluble in water; it is more soluble in dilute acids and very soluble in ethanol, chloroform and ethyl ether. ===Physical===
Availability
Delete this section if not applicable
Preparation
Benzocaine can be prepared by esterfication using 4-aminobenzoic acid and ethanol. It can also be prepared by reduction of ethyl 4-nitrobenzoate to the amine.
In industrial practice, the reducing agent is usually iron and water in the presence of a little acid.